The incidence of Minor β-thalassemia among Individuals participated in Premarital Screening Program in Ardabil province: North-west of Iran
محل انتشار: دوازدهمین همایش تازه های علوم بهداشتی کشور
سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 373
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شناسه ملی سند علمی:
IHSC12_172
تاریخ نمایه سازی: 13 مهر 1398
چکیده مقاله:
Background and Aim: The most effective way to prevent thalassemia is to screen for the disease at the population level and then to evaluate the molecularity of individuals. Considering the importance of minor β-thalassemia and its high prevalence in societies, the aim of this study was to investigate the prevalence of minor β-thalassemia in Individuals Referred to Genetic Laboratories in Ardabil province based RBC indices.Methods: This descriptive cross-sectional study was conducted on 39620 individuals participated in the national screening program for Minor β-Thalassemia. Of them 1925 cases had mean corpuscular volume (MCV) < 80 in one person or couple which referred to HbA2 concentration check. Results: Of all 1925 cases, 95 cases (4.93%) had HbA2> 3.5 and defined as Minor β-Thalassemia. The total incidence of minor β-thalassemia among all participated people was 2.4%. Of thalassemia cases 48.4% were women and 51.6% were men. Of all β-thalassemia cases, 49.5% live in Ardabil city and rest of them live in other cities. Conclusion: Results showed that the prevalence of minor β-thalassemia in Ardabil province was lower than country average rate and a study should be done in future for exact estimation of the disease.
کلیدواژه ها:
نویسندگان
Afshin Fathi
Assisstant prof in pediatrics. Ardabil university of medical science. Ardabil. Iran
Firouz Amani
Associate prof in biostatistics. Department of Pediatrics, Ardabil university of medical science. Ardabil. Iran