Antioxidant activities of seeds hydroalcohlic extract of Rumex obtusifolius

Introduction: Nowadays, the uses of herbal medicines have increased in the prevention and treatment of diseases in the world, especially Iran. The development of resistance in some Candida species and side effects of chemical drugs consumption new resources especially medicinal plants is very important.The purpose of this study was to investigate of antioxidant activities of hydroalcohlic extract from seeds of Rumex obtusifolius. Methods:The Rumex obtusifolius seeds were extracted using Ethyl acetate: methanol: distilled water (6:3:1) by Soxhelet system. The hydroalcoholic extraction of Rumex obtusifolius was evaluated for their antioxidant capacities using in vitro methods, including 1-diphenyl-2-picrylhydrazyl radical scavenging, β-Carotene bleaching test and reducing power assay. Total free phenolics, total flavonoids content were also examined. The components of extract were analyzed via GC-Mass instrument. Results: The hydroalcoholic extract can strongly scavenge DPPH radical and its antioxidant capacities which are high correlated with the total free phenolics and total flavonoids. This study revealed a highest antioxidant capacity in the seeds of Rumex obtusifolius as compared to the control groups. Conclusions: The extract includes very high amounts of phenolic compounds and antioxidant activity is indicated significant. This seems may be correlated to the presence of high levels of phenolic compounds, particularly pyrogallol.

کلیدواژه ها:

Rumex obtusifolius ، Antioxidant activity ، Hydro alcoholic extract