Hepatoprotective activity of Mammea africana ethanol stem bark extract

Jude Efiom Okokon; Michael Burata Bawo; Herbert Orji Mbagwu

Hepatoprotective activity of Mammea africana ethanol stem bark extract

محل انتشار: مجله گیاهان دارویی ابن سینا، دوره: 6، شماره: 2

سال انتشار: 1395

نوع سند: مقاله ژورنالی

زبان: انگلیسی

مشاهده: 360

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https://civilica.com/doc/930439

شناسه ملی سند علمی:

JR_AJP-6-2_012

تاریخ نمایه سازی: 1 مهر 1398

چکیده مقاله Hepatoprotective activity of Mammea africana ethanol stem bark extract

Mammea africana Sabine (Guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. The hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, total cholesterol, alanine aminotransaminase (ALT), aspartate aminotransaminase (AST), and alkaline phosphatase activities (ALP), antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH) and histopathological study of the liver. The administration of the stembark extract caused significant (p

کلیدواژه های Hepatoprotective activity of Mammea africana ethanol stem bark extract:

Medicinal plant ، Mammea africana ، liver-protective ، Antioxidant

نویسندگان مقاله Hepatoprotective activity of Mammea africana ethanol stem bark extract

Jude Efiom Okokon

Department of Pharmacology and Toxicology Faculty of Pharmacy, University of Uyo, Uyo, Nigeria

Michael Burata Bawo

Department of Pharmacology and Toxicology Faculty of Pharmacy, University of Uyo, Uyo, Nigeria

Herbert Orji Mbagwu

Department of Pharmacology and Toxicology Faculty of Pharmacy, University of Uyo, Uyo, Nigeria

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Adeneye AA, Olagunju JA, Benebo AS, Elias SO, Adisa AO, ...

Adjanohoun JE, Aboubakar N, Dramane K, Ebot ME, Ekpere JA, ...

Ali ZY, Atia HA, Ibrahim NH. 2010. Possible Hepatoprotective Potential ...

Balouchzadeh A, Rahimi H, Ebadollahi –Natansi A, MmaeiZongi B, Sabzeveri ...

Carpenter I, Mc Garry EJ., Scheimann F.1970. The neoflavonoids and ...

Carpenter I, Mc Garry EJ, Scheimann F. 1971. Extractives from ...

Chapius JC,Sordat B, Hostettman K. 1988.Screening for cytotoxicactivities of plants ...

Crichton EG, Waterman PG. 1978.Dihydromammea c/ob: A new coumarin from ...

Das K, Kathiriya AK 2012. Hepatoprotective activity of Stevia rebaudiana ...

Das S, Sarma G. 2009.Study of the hepatoprotective activity of ...

Davern II TJ, James LP, Hinson JA, Polson J, Larson ...

Dongmo AB, Azebaze AGB, Nguelefack TB. 2007.Vasodilator effect of the ...

Ellman GL. 1959. Tissue sulfhydryl groups. Arch Biochem Biophys, 82: ...

Farida T, Salawu OA, Tijani AY, Ejiofor JI. 2012. Pharmacological evaluation ...

Games DE. 1972. Identification of 4-phenyl and 4-alkylcoumarins in Mammeaamericana, ...

Gartlans JS, Key DB, Waterman PG, Mbi CN,Struhsaker TT. 1980. ...

Gilani AH, Jabeen Q, Ghayur MN, Janbaz KH, Akhtar MS. ...

Gupta AK, Chitme H, Dass SK, Misra N. 2006. Hepatoprotective ...

Hwang HJ, Kim IH, Nam TJ.(2008). Effect of a glycoprotein ...

Hutchinson LJ, Daziel JM.1958. Flora of West Tropical Africa, revised ...

Jaeschkea H, Bajta ML. 2010. Mechanisms of acetaminophen hepatotoxicity. Comp ...

Kanchana N and Sadiq AM. 2010. Hepatoprotective effect of Plumbago ...

Kosina P, Kren V, Gebbardt R, Geambal F, Ulrichava J, ...

Kouitcheu MLB, Kouam J, Penlap BV, Bonaventure TN, Fomum ZT, ...

Lawrence RA, Burk RF 1976.Glutathione peroxidase activity in selenium- deficient ...

Loki AL, Rajamohan T. 2003. Hepatoprotective and antioxidant effect of ...

Kuriakose GC, Kurup GM.2008. Antioxidant activity of Aulosira fertilisima on ...

Madani H, Talebolhosseini M, Asgary S, Naderi GH. 2008. Hepatoprotective ...

Mandade RJ. 2011. Hepatoprotective activity of ethanolic extract of Caesalpinia ...

Manokaran S, Jaswanth A, Sengottuvelu S, Nandhakumar J, Duraisamy R, ...

Marklund S, Marklund G. 1974. Involvement of superoxide anion radical ...

Marotta F, Yadav H, Gumaste U, Helmy A, Jain S, ...

Muriel, P. and M. Mourelle, 1990.Prevention by silymarin of membrane ...

Muriel, P., T. Garciapina, V. Perez-Alvarez and M. Mourelle, 1992.Silymarine ...

Nguelefack-Mbuyo EP, Dimo T, Nguelefack TB, Azebaze AG, Dongmo AB, ...

Nguelefack-Mbuyo PE, Nguelefack TB, Dongmo AB.2008. Anti- hypertensive effects of ...

Nkosi CZ, Opoku AR, Terblanche SE. 2005. Effect of pumpkin ...

Odukoya OA, Inya-Agba SI, Ilori O. 2007. Immune boasting herbs. ...

Okokon JE, Dar A., Choudhary MI. 2012. Immunostimulatory, anticancer, and ...

Okokon JE, Antia BS. 2007. Hypolipidaemic and cardioprotective activity of ...

Okokon JE, Davies K. 2014. Psychopharmacological studies of Mammea africana ...

Okokon JE,Antia BS,Osuji L,Udia PM. 2007. Antidiabetic and hypolipidaemic activity ...

Okokon JE, Udokpoh AE, Essiet GA. 2006. Antimalarial activity of ...

Okokon JE,Umoh E, Umoh U. 2009. Antiinflammatory and antinociceptive effects ...

Okokon JE,Umoh UF, Umoh EE,Etim EI. 2010. Antiulcer and antidiarrhoeal ...

Okokon JE, Bawo M.B 2014. Nephro- ...

protective effect of Mammea africana ...

against paracetamol induced kidney injury. J Herb Drugs, 5: 45-54. ...

Oyegbemi AA, Odetola AA. 2010. Hepatoprotective effects of ethanolic extract ...

Ouahouo BM, Asebaze AG, Meyer M, Bodo B, Fomum ZT, ...

Parmar SR, Vashrambhai PH, Kalia K. 2010. Hepatoprotective activity of ...

Plaa GL, Hewitt WR. 1989. Detection and evaluation of chemically ...

Prakash J, Gupta SK, Kochupillai V, Singh N, Gupta YK, ...

Raponda-Walker A, Sillans R.1961. Les plantesutiles du Gabon. Paris: Paul ...

Reitman S, Frankel S. 1957. Determination of Glutamate-Pyruvate transaminase (ALT) ...

Sinha AK. 1972. Colorimetric assay of catalase. Analytical Biochem, 47: ...

Yuan HD, Jin GZ, Piao GC. 2010. Hepatoprotective effects of ...

Zamani-Moghaddem E, Azami K, Minaeri-Zangi B, Mousau S, Sabzerari O. ...

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