Novel sol–gel-derived hardystonite-based biomagnetic nanoparticles for hyperthermia applications

Unique nanosized designed ceramic powders, Fe-doped hardystonite (Fe-HT) with the chemical composition of Ca1.85Fe0.15ZnSi2 O7 (0.15Fe-HT) and Ca1.75Fe0.25ZnSi2O7 (0.25Fe-HT), were synthesized by the sol–gel method in order to develop a multifunctional bioactive powder for hyperthermic and tissue engineering applications. Characterization techniques such as X-ray diffraction analysis, transmission electron microscopy, Fourier transform infrared spectroscopy and energy-dispersive X-ray spectroscopy were used to investigate the structural characterization of the obtained powders. The results showed that nanocrystalline single-phase Fe-HT powders were successfully synthesized by sol–gel method. The prepared nanopowders had structural properties such as crystallite size (~ 53 nm), crystallinity degree (~55 %) and lattice strain (~ 0.355 %) for 0.15Fe- HT and crystallite size (~ 40 nm), crystallinity degree (~ 41 %) and lattice strain (~ 0.401 %) for 0.25Fe-HT. The obtained Fe-HT nanopowders are expected to be a suitable candidate for tissue engineering and also hyperthermiabased cancer therapy.

کلیدواژه ها:

Fe doped ، Hardystonite ، Tissue engineering ، Cancer therapy