Effects of shilajit in improving burn in rats

IntroductionThe most important factor in healing wounds, especially, the wound of burn,is prevention of its infection. Most deaths from burn wound are as a result of entering of infection into the bloodstream. Pseudomonas aeruginosa is a major factor of infection in wounds. Shilajit is the natural compound derived from plants in the rocky mountainous. Research has shown this substance has inhibitory effect on Pseudomonas aeruginosa growth. According to role of this substance in traditional medicine and its application in the treatment of diseases, particularly fractures,ObjectivesThe aim of this study is to investigate the effects of shilajit on burn wound healing in rats.MethodsExperiments were done on three groups of mice that were burned, with 10 repetitions. The control group did not receive any restorative material. For other group, Shilajit solution with a concentration of 18 grams per deciliter was used for wound healing. For the third group was used Silversulfadiazine ointment on the burns. Percent improvement in different days of starting treatment, were calculated with the Feragson and Logan formula. Treatments were compared by using SPSS software.ResultsThe results showed that the use of Shilajit has statistically significant difference compared to the control and use of ointment.ConclusionIt seems this healing associated with Shilajit inhibitory effects on the growth of bacteria

کلیدواژه ها:

Shilajit ، Rat ، Burn