Association of inflammatory indices (NLR and PLR) as prognostic factors with anatomical variables in colorectal cancer pathology in patients attending to Booali and Resalat Hospitals in 2016-2017
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 366
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شناسه ملی سند علمی:
ACPLMED20_039
تاریخ نمایه سازی: 29 تیر 1398
چکیده مقاله:
Inflammation has a critical role in the pathogenesis and progression of colorectal cancer. Recent studies have shown that inflammatory markers such as neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) correlate with poor prognosis in colorectal cancer.In this research we aimed to investigate association of these markers with anatomical pathologic variablesof colorectal tumors. The present study retrospectively analyzed the data of 64 patients with colorectal cancer. NLR and PLR were significantly associated with poor tumor differentiation status. In conclusion, these inflammatory indexes can be introduced as a prognostic factors and help to more detailed stratification of colorectal cancer patients.
کلیدواژه ها:
Neutrophil to Lymphocyte ratio (NLR)- platelet lymphocyte ratio (PLR)- colorectal cancer- prognosis
نویسندگان
Minoo Saatian
Department of pathology,Islamic Azad University,Tehran Medical Branch
Vahid Talebi
Medical student ,Islamic Azad University,Tehran Medical Branch