The effect of serum levels of vitamin C on asthmatic children: a systematic review
محل انتشار: مجله پزشکی بالینی، دوره: 3، شماره: 3
سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 360
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شناسه ملی سند علمی:
JR_RCM-3-3_001
تاریخ نمایه سازی: 18 تیر 1398
چکیده مقاله:
Introduction: Asthma is a chronic inflammatory airway disorder that is distinguished by coughing, wheezing, and dyspnea. It is the most common chronic disease among children. Epidemiological trials have suggested that there may be a correlation between vitamin C intake and the incidence of asthma. Specifically, according to these studies, a rapid increase in the occurrence of asthma may be caused by a decreased intake of dietary antioxidants and various vitamins such as vitamin C. A systematic review was performed to determine the role that vitamin C, in terms of both dietary intake and serum levels, had on asthma in children. Methods: PubMed and Scopus databases were searched for studies that provide information on the effects of vitamin C on asthma in children aged between 1 and 17 years. The inclusion criteria specified that the studies involved needed to be cohort and case series involving at least ten patients. Exclusion criteria were non-English articles, case reports, and articles involving children who were aged below or above the age 1 and 17 respectively.Result: A total of 13 studies involving 6503 patients met the inclusion criteria. Dietary vitamin C intake was lower in people with asthma than in those without asthma. Lower quantity dietary intakes and serum levels of vitamin C were also associated with increased incidents of asthma.Conclusion: According to the extracted data, a relatively low dietary intake of vitamin C is associated with an increased risk of asthma and wheezing. Moreover, asthmatic patients who consumed vitamin C exhibited an improvement in their diseases.
کلیدواژه ها:
نویسندگان
Farhad Heydarian
Department of Pediatrics, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Hamid Ahanchian
Department of Allergy and Immunology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Maryam Khalesi
Department of Pediatrics, Emam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Saeed Ebrahimi
Department of Pediatrics, Emam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
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