Current Concepts in Scaffolding for Bone Tissue Engineering

سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 362

فایل این مقاله در 10 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_TABO-6-2_002

تاریخ نمایه سازی: 18 تیر 1398

چکیده مقاله:

Bone disorders are of significant worry due to their increased prevalence in the median age. Scaffold-based bonetissue engineering holds great promise for the future of osseous defects therapies. Porous composite materials andfunctional coatings for metallic implants have been introduced in next generation of orthopedic medicine for tissueengineering. While osteoconductive materials such as hydroxyapatite and tricalcium phosphate ceramics as wellas some biodegradable polymers are suggested, much interest has recently focused on the use of osteoinductivematerials like demineralized bone matrix or bone derivatives. However, physiochemical modifications in terms ofporosity, mechanical strength, cell adhesion, biocompatibility, cell proliferation, mineralization and osteogenicdifferentiation are required. This paper reviews studies on bone tissue engineering from the biomaterial point of viewin scaffolding.

نویسندگان

Toktam Ghassemi

Department of Chemical Engineering, Ferdowsi University of Mashhad, Mashhad, Iran

Azadeh Shahroodi

Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Mohammad H. Ebrahimzadeh

Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Alireza Mousavian

Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran