Individualization of controlled ovarian stimulation in IVF

The main reason for individualization of treatment in IVF is to suggest each woman the best protocol tailored to her own characteristics, to maximize the chances of pregnancy and preventing all the risks resulting from ovarian stimulation. Personalization of protocols for IVF should be based on the prediction of ovarian response for every individual. The starting point is to identify if a woman is likely to have a normal, poor or a hyper response and choose the ideal treatment protocol tailored to this prediction. The protocols, the dosage and even the gonadotrophin preparations and other adjuvant therapies may be different between groups. First of all , AFC and AMH, are the most sensitive markers of ovarian reserve identified to date, are ideal in planning personalized COS protocols. In this lecture we will define the starting point which is to identify normal, poor or a hyper responders and to choose the ideal treatment protocol tailored to this prediction.