Application of poly-Alizarin red s/ Multi-Walled Carbon Nanotubes-Modified electrode for detection of tramadol and dopamine

A new electrochemical sensor for the fast and simultaneous determination of tramadol (TRA) and dopamine (DA) was developed based on modification of carbon glassyelectrode (GCE) with alizarin red s (ARS) and multi-walled carbon nanotubes (MWCNTs) was developed. Electrochemical methods including cyclic voltammetry (CV) and choronoamperometry (CA), differential pulse voltammetry (DPV) were used to characterize the processes of electro polymerization and electrochemical determination. Under the optimized experimental conditions, TRA and DA have linear responses in the ranges of 10-2250 M and 0.1-200 M, respectively, and the detection limits is 0.64 M and 0.056 M respectively. In addition, the modified electrode was employed for simultaneous detection of TRA and DA. The analytical efficiency of this sensor has been measured for the detection of TRA and DA in human serum with good results [1,2].