Synthesis of pyrido[1,2-b][1,2,4]triazine-7,9-dicarbonitrile derivatives

Heterocyclic compounds attract significant attention in the chemical literature due to their abundance in natural products and their diverse biological properties [1, 2]. Indole is the most important chemical skeletons which existing as the main core in the structure of various physiologically, pharmaceutically, and industrially important compounds [3]. In this investigation reaction of 2-hydroxy-2-(1H-indol-3-yl)-1- phenylethan-1-one derivatives 3 and 1,6-diamin derivatives 4 in the presence of acid catalyst lead to the corresponding products 5 and 6 in 85-92% yields. The structures of compounds were confirmed by spectroscopic and analytical data