Evaluation of Overall Survival and its Influencing Factors in Patients with Chronic Lymphocytic Leukemia in West of Iran in 1998-2016

Background Aim: Chronic lymphocytic leukemia (CLL) is the most common lymphoidleukemia in Western Countries. Also, in Asian countries, such as Iran is expanding. This study wasinvestigated in Kermanshah province in 73 patients newly diagnosed with chronic lymphocyticleukemia, and the aim of this paper is the evaluation of overall survival (OS) rate and the factorsaffecting it.Methods and Materials: This is descriptive-cross sectional study on 73 patients with CLL during1998-2016 and patients were classified according to clinical symptoms, age mean, sex, laboratoryfindings, diagnostic tests, the therapeutic regimens and side effects from them. Data were enteredinto SPSS, CAN-Reg4 and all tests were performed at the 5% level of significance using SPSSversion 17.0. Patients with CLL have referred to related clinical oncologist have been evaluated inour paper from Kermanshah province during 18 years.Results: According to our findings from this study the mean age of the patients at diagnosis was59.58 years that 53.4 were male. Mean of OS in patients was 175.53 months, in detail, mean ofsurvival in 39 male patients was 128.52 months and in 34 female patients was 190.66 months. Also,OS was associated with the stage of disease (CLL), sex and treatment. The 5-year survival and theten-year survival rate of patients were 89% and 81%, respectively.Conclusion: According to recently progression in CLL treatment, but this malignancy stillincurable and this is an important point for the evaluation of survival rate in this patients. Based on our findings in addition to significantly increasing in OS, related factors also is important andefficient on OS.