The Long Term Follow up on p32 Colloid Radiosynovectomy for Haemophilic Synovitis

BackhroundsRepeated intra articular bleeding with subsequent development of chronic synovitis andcartilage changes. Radiosynovectomy is a familiar therapeutic choice in managementof chronic synovitis in haemophilia The aim of this study was Long Term Follow up onp32 Colloid Radiosynovectomy for Haemophilic Synovitis.MethodsThis a observation study on 46( 43) patients who under went p32 ColloidRadiosynovectomy for Haemophilic Synovitis. The Lost to follow was happen for 3patients. In this article 55( 52) joints were assay . P32 snoviorthesis protocol was 1 mCifor Knee and 0.5 mCi for other jointsResultsThe Mean age was 43-19( 30.2) and the mean of Follow up duration was 14.9y(Longest FU ever reported in the literature) , the Distribution joint s were included44 knee, 7 ankle, 1 elbow(Type: 46 A ,4 B , 2 VWB.The mean of Range of motion and Flexion Contracture was4.74 , 119.21 ,at time of synoviorthesis and Range of motionand Flexion Contracture was 10.13 , 114.74 at 15y follow up , so Range of motionand Flexion Contracture had shown a significant difference during both times. Inlatest follow-up(14.9y) %67 of patients reported at least a %50 decrease in bleedingfrequency after treatment. WFH Pain score decrease in long term follow up from 2.6 to1.03(P value:0.002) after synoviorthesis. For seven joints, TKA surgery was performed(%16). Three reinjections 11m/10yrs/15yrs after initial procedure were reported. dueto FC, for two joints, distal femoral trapezoid extension osteotomy was performed.ConclusionsRadioactive synoviorthesis highly effective , decreases both the frequency and theseverity of hemarthrosis , P32 synoviorthesis has a long lasting effect on Reductionof bleeding and Pain . in our study %64 of patient reported pain less or minimal pain,Radiographic worsening continue to progress and ROM Decrease significantly after along period of synoviorthesis. P32 synoviorthesis at earlier age(stage) is associated withbetter outcome. The mean age of patients at time of synoviorthesis was significantlydifferent in the two groups that had joint replacement compared with other patients.