The Effect of Pap Smear on Diagnosis of Cervical Neoplasia in Qazvin in 1396

Background: During the past 60 years, Pap smear has shown remarkable success in many countries in the field of screening and early diagnosis of cervical cancer, but cervical cancer is still the fifth most common cancer in Iran. The aim of this study was to evaluate the value of Pap smear in the diagnosis of cervical neoplasia in comparison with the findings of cervical biopsy as a diagnostic standard.Materials and Methods: In this cross-sectional study, all volunteer non-migrant women who performed routine pap smears were interviewed at the Qazvin hospitals clinics during the years 94-96 and performed colposcopy based on clinical findings and diagnosis of colposcopist diagnosis. they started studying. Patients with pap smear were given colposcopy and biopsy simultaneously. Sensitivity, specificity of Pap smear test in diagnosis of cervical neoplasia in comparison with cervical biopsy findings was calculated as gold standardResults: According to the results of pathology of cervical biopsy in 57% of patients, there were abnormal findings including viral papillomavirus and grape 1, 2 or 3 neoplasia. While only 21% of the people found abnormal Pap smears. Based on the comparison of the results of pap smear and the pathology of cervical biopsy, the sensitivity of Pap smear to detection of cervical neoplasia was 20.9%, its specificity was 74.8%.Conclusion: The lower sensitivity and specificity of pap smear in this study than the other reports presented in the world, may require more qualitative control of the stages of pap smear, including sampling, preparation and interpretation of samples. It is also suggested that similar studies be done with more samples in other centers, especially health care centers in Iran.

کلیدواژه ها:

pap smear ، cervix ، cervical neoplasia ، screening test