NUTRITIONAL AND LIFESTYLE DETERMINANTS OF NON-COMMUNICABLE DISEASES IN ADULTS; RESULTS FROM RANCD COHORT STUDY

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 469

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شناسه ملی سند علمی:

INC15_457

تاریخ نمایه سازی: 30 دی 1397

چکیده مقاله:

Background and Aim: Following reduction of communicable diseases, changing lifestyle and increasing undesirable habits including inactivity and non-healthy eating behaviors has increased the risk of non-communicable chronic diseases such as diabetes, heart disease, osteoporosis, and metabolic syndrome. This study aimed to determine the relationship between non-communicable diseases and their risk factors with lifestyle in adults Ravansar Methods: Ravansar Non-Communicable Diseases (RaNCD) cohort study was performed on 10063 men and Women, aged between 35-65 years. Data was collected using blood samples, food validated frequency, dietary habits questionnaire. Medical examinations and anthropometric measurements also performed. Blood samples were analyzed with appropriate standard laboratory methods. Statistical analysis was performed using chi-square test, simple linear regression, multiple linear regressions and logistic regression. The prevalence of heart disease, osteoporosis, fatty liver, psychiatric disorders, depression and asthma was higher in women compared to men (P<0.001). The prevalence of nonalcoholic fatty liver was 7% in urban and 3.4% in rural population (P<0.001). The prevalence of depression was higher in urban areas compared to rural areas (2.2 V 1.1, P=0.05). After adjusting for age, gender and dietary factors, logistic regression showed physical activity as a protective factor that reduced the risk for development of metabolic syndrome, diabetes, dyslipidemia, and hypertension. With adjusting for age, gender, nutrition, and economic status, the odds for developing metabolic syndrome reduces by 13% in subjects who exercise an extra one minute per day (P<0.001). The odds for developing dyslipidemia reduced by 11% in men and by 12% in women with every extra minute of physical activity per day (P=0.07).The odds for developing metabolic syndrome and type II diabetes was greater in economically higher participant than those in deprived status (P<0.001). Smaller household size, higher education, higher per capita reading and rural living are among factors that reduce the odds for developing metabolic syndrome and type II diabetes (P<0.001). Consumption of trans fatty acids, PUFA and MUFA was significantly associated with dyslipidemia. Every gr increased in trans fatty acids, increased the triglyceride by 0.12 mg/dl (P<0.001). Every gr increase in Monounsaturated fatty acids, increased the triglyceride in subjects by 0.28 mg/dl (P<0.001). Every gr increase in fiber intake, decreased the fasting blood sugar in subjects by 0.013 mg/dl, which was significant (P<0.001). High intake of fat (ß=032, p=0.001) and carbohydrates (ß=0.056, p<0.001) in the diet was significantly associated with increased risk of hypertension. After adjusting for confounding variables, the risk of dyslipidemia increased by 7.8 times for every extra unit of BMI, and by 2.1 times for every additional percentage of body fat. The odds for developing metabolic syndrome increased by 16% (P<0.001) for every extra unit of BMI, and by 5.2% for every additional unit of WHR (95%CI, 3.6-6.8; P<0.001). The odds for developing dyslipidemia in urban men was 38% greater than rural men (P=0.01), and in urban women 85% greater than rural women (P<0.001). The prevalence of asthma (2.8 V 1.5, P=0.005), hypertension (3.2 V 1.5, P<0.001), diabetes (5.4 V 2.7, P<0.001) and psychiatric disorders (1.4 V 0.6, P=0.009) were significantly higher in urban population compared to rural population. The odds for developing fatty liver was greater by 21% (P<0.001) in men and by 15% (P=0.02) in women from higher economic status compared to men and women from poorer classes. The odds for developing thyroid gland disorders was significantly higher in subjects with higher education and from higher economic classes (P=0.002).Conclusion: The risk of non-communicable diseases has a significant relationship with lifestyle, especially physical activity, dietary intake and body composition. Obesity was a major risk factor for developing chronic diseases. Living in rural area showed a protective factor against chronic diseases. The prevalence of chronic diseases was higher in women compared to men and in urban population compared to rural population. This large sample size cohort study reviled that inactivity being overweight and obese and living in urban are the major life treating and increasing non-communicable chronic diseases.

نویسندگان

Yahya Pasdar

Research Canter for Environmental Determinants of Health, Kermanshah University of Medical Sciences,Kermanshah, Iran

Farid Najafi

Research Canter for Environmental Determinants of Health, Kermanshah University of Medical Sciences,Kermanshah, Iran

Behrooz Hamzeh

Research Canter for Environmental Determinants of Health, Kermanshah University of Medical Sciences,Kermanshah, Iran

Hossein Poustchi

Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran