Study of Bacterial Aetiology and their Antibiotic Susceptibility Pattern in Otitis media

Background: Otitis media is inflammatory response of middle earthat is caused by various factors such as infection and dysfunction of Eustachian tube. This disease is one of the most common chronic infectious diseases in the world; and if it is not treated and followed accurately, causes severe and irreversible damage. Methods: In this review article, the comprehensive search was conducted in PubMed, Scopus, Science Direct, Ovid, Web of Science, SID and Magiran, with using Otitis media, Bacterial agents, and Antibiotic resistance keywords. Of the articles that have been published since 2010 to 2016, 19 articles were selected and studied. Results: The most common isolated bacteria were:Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis and Streptococcus pneumoniae.There was a significant relationship between the type of bacteria isolated from Otitis Media with the presence of allergies.Among antibiotics, Pseudomonas aeruginosa as the most common bacteria, had the highest susceptibility to Amikacin, Gentamicin Sulfate and Ciprofloxacin, and the highest resistance to Cefixime and Co-trimoxazole.Staphylococcus aureus as the second most common bacteria, hadthe highest susceptibility to Vancomycin and the highest resistance to Co-trimoxazole, Ampicillin and Oxacillin Sodium. Conclusion: Given that Pseudomonas aeruginosa and Staphylococcus aureus are the most common pathogens in otitis media; In cases where middle ear culture is not feasible, use of Amikacin, Gentamicin Sulfate, Ciprofloxacin and Vancomycin antibiotics is recommended for treatment.

کلیدواژه ها:

Otitis media ، Bacterial agents ، Antibiotic resistance