Investigating the Effects of Lactobacillus Delbrueckii on Blood Sugar and Insulin Level in Diabetic Mice
محل انتشار: پنجمین کنگره باکتری شناسی پزشکی ایران
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 454
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شناسه ملی سند علمی:
MBMED05_028
تاریخ نمایه سازی: 1 دی 1397
چکیده مقاله:
Background: Lactobacilli are gram positive microorganisms that are beneficial for human health. They are often found in materials like probiotic dairy or supplements. According to some studies, Lactobacilli play a significant role in improving symptoms of diabetes and reducing blood sugar level. The present study probes into the effects of oral administration of Lactobacillus Delbrueckii on reducing blood sugar level in diabetic mice. Methods: In this study, 28 Syrian female mice were supplied. Then, 14 of them (weighing 180 mg/kg) were made diabetic through intraperitoneal injection of streptozocin. After 7 days, a blood sugar test was applied to verify their being diabetic. One group of the mice was fed with Lactobacillus Delbrueckii and carrot juice. The second diabetic group, on a daily basis, was treated with only carrot juice with no Lactobacillus Delbrueckii. The blood sugar level and signs of improvements in all of the groups were considered weekly. After four weeks, the mean of blood sugar and insulin serum levels in different groups were compared. Results: The obtained results showed that in comparison with the control group, the symptoms of diabetes (Polyuria and Polydipsia) and blood sugar level in diabetic mice fed withLactobacillus Delbrueckii improved significantly. Conclusion: Investigation of insulin level in the mice treated with Lactobacillus Delbrueckii showed that they increased significantly in comparison with that of the control group.
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نویسندگان
Yones Parvin
Maragheh University of Medical sciences
Asghar Tanomand
Maragheh University of Medical sciences
Hamid Mostafazadeh
Maragheh University of Medical sciences