Collagen Matrix Dressing in Treatment of Diabetic Foot Ulcer

Diabetic foot Ulcer (DFU) is one of most complicated life and limb-threating may happen following diabetes mellitus. These ulcers often delayed to heal despite of all standard care methods and the healing outcomes are mostly unacceptable. In such complicated healing process, any advanced wound care to promote complete healing is recommended. The collagen matrix dressings have potential to promote regenerative process. In this study, the efficacy of collagen matrix dressings were compared with standard dressing for wound healing in patients with DFU. After standard care including debridement, infection control and off-loading, the patients were randomly received either a collagen matrix dressing or saline-moistened gauze dressing for wound care. Our results showed that these advanced dressing could considerably improve healing rate of chronic diabetic foots. Frequency of complete healing rate in a period of 24-weeks follow-up will be significantly better in collagen matrix dressing group.