Effect of Low Level Laser Therapy on the Healing Process of Donor Site in Patients with Grade 3 Burn Ulcer after Skin Graft Surgery (a randomized clinical trial)

Background: Skin graft is standard therapeutic technique in patients with deep ulcers but managing donor site after grafting is very important. Although several modern dressings are available to enhance comfort of donor site, using techniques that accelerate wound healing may enhance patient’s satisfaction. Low Level Laser Therapy (LLLT) has been used in several medical fields, including healing of diabetic, surgical and pressure ulcers but there is not any report of using this method for healing of donor site in burn patients. In this study for the first time we evaluate the effects of LLLT on the healing of donor site in these patients. Materials and Methods: The protocols and informed consent were reviewed according to Iranian Registry of Clinical Trials (IRCT2016020226069N2). 18 donor sites in 11 patients with grade 3 burn ulcer were selected. Donor areas were divided into 2 parts, for laser irradiation and control randomly. Laser area was irradiated by red, 650 nm laser light, 150 mW, radiation area: 0.25 cm2, power density: 0.6 W/cm2, 2 J/Cm2, continuous mode, 16-20 point, 10 sec each point, (Canadian Optic Laser Center, COL laser, Canada) direct in-contact probe. To avoid contamination a sterile, transparent cover was used. Output laser power after passing through the cover was calculated using dosimeter. Treatment was done on day 0 (immediately after surgery), 3, 5, 7 and 9 (5 sessions). Dressing and other therapeutic cares for both sites were the same. Patient and the person who analyzed the results were blinded. Results: The size of donor site reduced in both groups during the 7 days study period (P<0.01) and this reduction was significantly greater in laser group (P=0.01). Discussion: In the present study for the first time we evaluate the effects of LLLT on the healing process of donor site in burn patients. The results showed that local irradiation of red laser light can accelerate wound healing process significantly.

کلیدواژه ها:

Low Level laser Therapy ، Skin Graft ، Wound Healing