Prevalence rate of skin HPV types of 2, 3, 4, and 5 among patients with lichen-planus versus control group

سال انتشار: 1396
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 475

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شناسه ملی سند علمی:

ACPLMED19_004

تاریخ نمایه سازی: 20 آبان 1397

چکیده مقاله:

Introduction: Lichen planus is an idiopathic papulosquamous skin disease with purple itching papules mainly in extremities in leading to decreased quality of life and numerous problems in affected patients. Among the possible causes are viruses. Hence in this study the prevalence rate of HPV types of 2, 3, 4, and 5 was determined and compared among patients with lichen-planus and control group. Material and Method: In this case-control study, 28 consecutive patients with lichen-planus and 25 healthy subjects were enrolled. The prevalence rate of HPV types of 2, 3, 4, and 5 and existence of more than one type of HPV were determined by PCR method and compared across the groups. Result: There were 50% and 84% HPV-2 positive samples in case and control groups, respectively showing significant difference (P=0.009). Also 42.9% in case and8% HPV4 positive cases in case and control groups, respectively showing significant difference (P=0.004). Also the HPV types of 3 and 5 and existence of more than one HPV type were not significantly differed across the groups (P > 0.05). Conclusion : Totally it may be concluded that presence of some HPV types in lichen-planus patients is higher than control group ant lack of HPV type 2 and presence of type 4 may be risk factors for lichen-planus.

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نویسندگان

Zahra Jahangiri

department of pathology,Iran university,Tehran,Iran

Nasrin Shayanfar

department of pathology,Iran university,Tehran,Iran

zahra shahhosseini

pasteur institute,Tehran,Iran

kayhan azadmanesh

pasteur institute,Tehran,Iran