Ciliated hepatic foregut cyst, two case reports in children and review of the literature

Ciliated hepatic foregut cyst (CHFC), a rare foregut developmental malformation, usuallypresents as a solitary, unilocular or occasionally multilocular cyst in the liver. This congenitallesion is rare and is mostly diagnosed in adults, with estimated 100 cases reported in theliterature. Only 10 cases were reported in children in our review of English Medicalliterature. Patients are usually asymptomatic and they are mostly detected incidentally onradiologic imaging or during surgical exploration. However, patients may present with portalhypertension, obstructive jaundice, and they may even present with malignancy, whichhappens in 3% of cases. Vague right upper quadrant pain, nausea, and vomiting are the mostcommon symptoms.We present two cases of CHFC in two 3.5-year-old boys, one of them had cystic lesion atmedial segment of left lobe of liver (common site), and the other one was located at right lobeof liver (less common site). Histologically, both cysts had four layers composed of innerciliate, pseudostratified, columnar epithelium, subepithelial connective tissue, smooth musclelayer, and an outer fibrous layer. These are the first pediatric cases to be reported from Iran.

کلیدواژه ها:

Ciliated hepatic foregut cyst ، liver cyst