Porokeratotic Eccrine Ostial and Dermal Duct Nevus

Introduction:PEODDN is a rare benign cutaneous disorder that clinically resembles comedo nevus butfavors the palms and soles; where pilosebaceous follicles are absent. Widespreadinvolvement along Blaschko’s lines can also occur. It is a disorder of keratinization involvingthe intraepidermal eccrine duct (acrosyringium) and is characterized by eccrine hamartomaand cornoid lamellation in pathology.Case presentation:The patient is a 29-year-old man with an 8-year history of pruritic skin lesions on his rightlateral ankle. In the pathologic examination, multiple small epidermal invagination withoverlying parakeratotic cornoid lamellation, loss of granular layer, and few dyskeratotic cellsat the base of epidermal invagination are revealed. After clinic-pathologic correlation thediagnosis of Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) was made.Discussion:Late-onset and rare clinical presentation as pruritic lesion are the characteristic features thatmake this patient as an extraordinary presentation of PEODDN.

کلیدواژه ها:

Cornoid Lamella ، Porokratosis ، Eccrine Hamartoma ، Porokeratotic Eccrine Ostial and Dermal Duct Nevus