The Effect of Aquae Extract of Aloe Vera on Expression of Acetylcholinesterase (AChE) After Spinal Cord Compression inAdult Rats

سال انتشار: 1392
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 324

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شناسه ملی سند علمی:

ACPLMED15_037

تاریخ نمایه سازی: 20 آبان 1397

چکیده مقاله:

Introduction:Prevalance of SCI is fast growing.In this study we evaluate the effect of Aloevera gelinsaving of motoneurons and expressing the Acetylcholinesterase enzyme.Materials and Methods:32 adult Sprague-Dawley rats were randomly divided into 4 groups:1-Laminectomy+salineinjection. 2-Laminectomy +Aloevera injection. 3-SCI + Aloevera injection. 4- SCI+salineinjection. Examination of Acetylcholinesterase enzyme was performed by counting themotoneurons based on using immunohistochemical technique.Result:4 weeks after laminectomy,results indicated compression reduce number of motoneurons.Aloevera gel mitigates reduction in number of motoneurons.It also helps to increase theAcetylcholinesterase enzyme after SCI.Conclusion:Unknown neuroprotective effects of Aloevera coming from its anti- inflammatory andneuroprotective properties are in charge of the observed decrease in the number of deadmotoneurons,amd subsequent increase in Acetylcholinesterase after SCI.

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نویسندگان

Marjan Heshmati

Faculty of Medicine,.Shahed University

Mohammad Reza Jalali

Faculty of Medicine,.Shahed University

Zohre Khodashenas

Faculty of Medicine,.Shahed University