Immunohistochemistry in Lung Cancers

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 334

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شناسه ملی سند علمی:

LCPIMED03_011

تاریخ نمایه سازی: 5 آبان 1397

چکیده مقاله:

Immunohistochemistry plays a critical role in the classification of tumors into subtypes andfor assessing biomarkers for accurate therapeutic decision. Immunohistochemistry is a widelyavailable technique that is less challenging and can provide clinically meaningful results quicklyand cost-efficiently in comparison with other techniques.Pathologists are required to classify lung cancer into specific subtypes and assess biomarkersrelevant to molecular-targeted therapies.This lecture summarizes the hot topics of immunohistochemistry in lung cancer, including:1- Adenocarcinoma versus squamous cell carcinoma2- Neuroendocrine markers3- Lung carcinoma versus malignant mesothelioma4- Metastatic carcinoma versus primary lung carcinoma5- ALK, ROS1, EGFR and PD-L1Major pitfalls in evaluating immunohistochemical results are also described.

نویسندگان

Mitra Heydarpour

M.D, Associate Professor of Pathology Isfahan University of Medical Sciences, Isfahan, Iran