SURVEY AND COMPARISON OF THE EFFECT OF MULTIPLE LACTOBACILLUS ON THE FUNCTION OF LIVER ENZYMES IN THE VISTAR MATURE NAFLD RATS

Background and Aim:In recent years, changes in lifestyle have led to an increase in plasma lipids and a change in the level of Non-Alcoholic Fatty Liver Disease (NAFLD) and cardiovascular disease. Considering the beneficial and non-pathogenic effects of lactobacillus, we used this study.Methods:In this research, rats were used, first, hypercholesterolemia and then NAFLD disease. Then the amount of cholesterol and triglyceride serum levels of enzymes AST, ALT and ALP were examined. Then, the effects of L.Casei and L.Plantarum strains suspension were studied.Results:The effect of L.Casei strain on the other is more in reducing the level of cholesterol and triglyceride. In contrast to the hepatic enzymes, L.Casei strain showed a significant difference in the level of AST and ALT enzymes, but in relation to The ALP enzyme was not significantly different.Conclusion:Lipid metabolites had significant reductions, indicating the potent effects of probiotic bacteria on continued use of cholesterol, triglyceride and liver enzymes in rats. This point indicates that lactose in the diet of organisms and lactic acid is produced positive by the presence of the beta-galactosidase enzyme in probiotic bacteria, thus preventing the storage of fat and adipose tissue in the body.

کلیدواژه ها:

L.Casei ، L.Plantarum ، NAFLD ، Cholesterol ، Triglyceride