SYNTHESIS, PREPARATION, CHARACTRIZATION AND ANTIBACTERIAL PROPERTIES OF AG/PLA NANOFIBER

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 417

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شناسه ملی سند علمی:

MEDISM19_619

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:In the past two decades, the field of nanotechnology has grown exponentially since its birth and has made an immense impact on physical, chemical, earth and biological sciences [1–5]. There has been an immense extension of nanomaterial applications and uses as a result of basic and applied research from scientists all over the world. One such class of nanomaterials are the metal oxide (MeO) and metal sulfides (MeS) nanoparticles (NPs), ranging in size from 1 to 100 nm and available in different shapes and sizes.Methods:Ag/PLA Nanofiber synthesized by nanoemulsion assistance with electrospinning method. 50 mg of AgNO3 and 200mg polylactic acid were precursors to getting started. In a typical and the creative method at the first stoichiometric amount of Tween 80, 60 as surfactant phase and Span 20, 40 as cosurfactant phase (1:1) were dissolved in 20ml deionized water under vigorous stirring for 2 h using a magnetic stirrer at room temperature. After formation of Ag nanoemulsions, we loaded this nanoemulsion on PLA NanofiberResults:To prepare 100 ccs of the medium, weigh the Hinton broth 2.1 grams, and in another 500 ml, it dissolves and dissolves. Then we make microbial leachate from the tested microorganisms and compare with the half McFarland their turbidity, to the extent that they are half McFarland. Then, with a micropipette of 2.5 microns from the lagoon, remove the bacteria on the plates, and finally place the plates in the incubator for 24 hours, and the next day the results are read.Conclusion:we found that 32% of nanoparticles prevents

کلیدواژه ها:

Nanostructures ، Ag/PLA Nanofiber ، Antibacterial Properties ، Gram Positive and Negative Bacteria

نویسندگان

Mohammad Hassan Moshafi

Department of Pharmaceutics, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran

Mehdi Ranjbar

Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran