STUDY OF EPSTEIN-BARR VIRUS (EBV) IN CHILDREN UNDER 5 YEARS SUSPECTED TO INFECTIOUS MONONUCLEOUS

Background and Aim:Epstein-Barr virus of the herpes virus family and subfamily of Gamaherpes Virinea. Infection with this virus is common throughout the world, in developing countries, more than 90% of children up to the age of 6 months, to become infected. This virus is a major cause of infectious mononucleosis disease, with symptoms such as headache, malaise, fatigue and sore throat occur.Methods:60 children with symptoms of infectious Mononucleous, blood were collected And serum was separated after 15 minutes of centrifugation. Then tested for EBV IgM, by closed ELISA system Alegria company, was laid. To verify that their positive, Monotest (Rapid method) and CBC Diff for the presence and amount of large lymphocytes, which was known as Atypical lymphocytes carried out.Results:In 10 cases (16.67%) boys and 8 patients (13.34%) were female and total 18 patients (30%) were positive for IgM test. Monotest was positive in all cases Peripheral blood smear these patients, atypical lymphocytes was observed, while their value on average was about 3.2. Positive test, no significant relationship with genderConclusion:As we can see, all these tests, each, confirmatory tests are good for each other and And monotest and observe atypical lymphocytes Can help in positive cases EBV IgM antibody and suspected infectious Mononucleous.

کلیدواژه ها:

EBV ، children ، Infectious Mononucleous