PREVALENCE OF HELICOBACTER PYLORI IN PATIENTS WHIT COLORECTAL CANCER

Background and Aim:Colorectal cancer (CRC) is the growth of cancer cells in the colon or rectum. There are many risk factors associated with colon cancer . one of the risk factors is Microbial infection such as Helicobacter pylori. H.Pylori is one of the most commonly gastrointestinal infections and colonizes the stomach of man and induces severe mucosal inflammation. Recent studies have shown a relation between Helicobacter pylori infection and the risk of colon cancer. However, the results of this study are controversial. The aim of this study was to assess the association between Helicobacter pylori infection and the risk of colon cancer in IranMethods:: From 2016 to 2017, biopsy samples were obtained from patients suspected of colorectal cancer .In the next step ,DNA was extracted by Commercial kit .Then for the gene glmM Helicobacter pylori was performed PCR method and finally the data was analyzed.Results:At total 86 patients that 18 were control and 68 were cancer patients was studied .This study included 32.6% females and 62.8% males (Mean age 56.4 years; age range 21 to 87 years) .Of 86 biopsy specimens all of them were negative for H. pylori (P < 0.05).Conclusion:Although in studies has been suggested role of the H. pylori in CRC but we didn’t find any association among H.pylori and Iranian patients.

کلیدواژه ها:

Helicobacter pylori ، colorectal cancer