MUTAGENIC,ANTI MUTAGENIC ACTIVITIES AND ANTIBACTERIAL EFFECTS OF 3 JUNIPERUS BY AMES METHOD USING SALMONELLA TYPHIMURIUM STRAIN

Background and Aim:Today, the problems caused by the effects of synthetic and chemical drugs on the researchers have led to the investigation of the properties of various plants. All three Juniperus Sabina, Juniperus excelsa, Juniperus communis are from native species Iran and its methanolic extract has an antibacterial effect, we first developed the antimicrobial effect of these three species against Salmonella enteritidis and Yersinia enterocolitis and Campylobacter jejuni using a well plate and microplate method to determine the diameter of the inhibition zone and MIC and MBC. Also, we determined the mutagenicity and anti mutagenicity of this plant.(AIMS Test)Methods:cross sectional,observational study,basic AppliedResults:under our experiment ,in mutagenicity test,it was not any mutagenic effect with or without s9 for j.sabina,& j.excelsa & j.communis but the antimicrobial effect of these three species against salmonella enteritidis(ATCC13111)and yersinia enterocolitis(ATCC22079)and campylobacter jejuni (ATTC 33560) is goodConclusion:based on antimicrobial &mutagenicity (AIMS)test effect results, doing other in vivo and in vitro complementation tese are recommended for the further studies

کلیدواژه ها:

mutagenicity ، anti mutagenicity ، antibactrial activity ، salmonella enteritidis ، yersinia enterocolitica ، juniperus