IRANIAN NATIVE HONEY AS A ROBUST AGENT IN GREEN SYNTHESIS OF SILVER NANOPARTICLES WITH ANTIBACTERIAL FEATURES

Background and Aim:Honey, as a precious gift from nature, has historically been involved in the human diet. Although this natural product has a high potential to combat a variety of diseases, especially infectious diseases, use of this substance in therapeutic processes directly, faces some limitations.Methods:In this study the potential of Astragalus gossypinus honey in the green synthesis of silver nanoparticles has been investigated, as the interface of agricultural science, nanotechnology, and biomedicine. UV-Vis, XRD, DLS, FE-SEM, and FT-IR were used to the physicochemical characterization of productsResults:Based on the result, Astragalus honey plays an efficient role in the synthesis and stabilizing of silver nanoparticles (spherical, 42.7 nm), although it doesn’t show significant antibacterial activity against investigated strains. The resulted nanoparticles have significant antibacterial activity against E. coli, P. aeruginosa, and S. aureus bacterial strains even at low concentrations (MIC= 24.5 µg/mL) and their activity is concentration dependent as well.Conclusion:The results of this investigation revealed that Astragalus honey as a Natural Agent plays an efficient role in the synthesis and stabilizing of monodisperse silver nanoparticles. This green synthesis method is eco-friendly, low cost and applicable, in addition, silver nanoparticles synthesized by this method have good physicochemical properties and antibacterial behavior, although Astragalus honey doesn’t show significant antibacterial activity in this study.

کلیدواژه ها:

Iranian Native Honey ، Green Synthesis ، Silver Nanoparticles ، Antibacterial Agent