THE COMPARISON OF ZOUSH OINTMENT WITH SILVER SULFADIAZINE OINTMENT IN BURN WOUND INFECTION

Background and Aim:Increasing the resistance of Pseudomonas aeruginosa to antibiotics brings about infection control in patients with burns. Burn is considered to be one of the worst medical conditions that, in addition to causing damage to all physical and mental dimensions, is able to infect at all ages.(1)Methods:ZOUSH ointment was formulated with natural ingredients. In 80 mice, burn was induced by Ian Allen Holder. Two treatments per day and 20 days with silver sulfadiazine and ZOUSH ointment were performed in two separate groups.Results:In the treatment group with silver sulfadiazine ointment, the average number of Pseudomonas aeruginosa isolated at exit 2 was significantly higher than Exit 1. At the interval between exit 1 and 2, two of the mice die of this group, which could be due to a sudden increase in the average number of bacteria and, consequently, the inability of the body and the silver sulfadiazine ointment used to control the infection, which eventually resulted in death. Also, the mean number of Pseudomonas aeruginosa isolated in the treatment of silver sulfadiazine ointment group from the 10th day was reduced, but the effect of bactericidal was significantly higher in the ZOUSH ointment group, so that the average number of Pseudomonas aeruginosa isolated after 15 days Treatment with silver sulfadiazine ointment group is even more than the average number of Pseudomonas aeruginosa isolated after 5 days of treatment with ZOUSH ointment group.Conclusion:These results indicate that bactericidal has a ZOUSH ointment with an effect more than triple, the silver sulfadiazine ointment.

کلیدواژه ها:

ZOUSH ointment ، Silver sulfadiazine ، wound infection