EVALUATION OF ANTIBIOTIC RESISTANCE OF ACINETOBACTER BAUMANNII STRAINS ISOLATED FROM CLINICAL SAMPLES OBTAINED IN ZAHEDAN HOSPITALS

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 350

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شناسه ملی سند علمی:

MEDISM19_200

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:Acinetobacter baumannii is a major cause of nosocomial infections. It has the ability to develop resistance to antibiotics quite easily. The present study aimed to evaluate the patterns of antibiotic resistance of different clinical isolates of A.baumannii.Methods:Acinetobacter baumannii strains were isolated from sixty clinical samples obtained from 3 hospitals of Zahedan during January to May 2018. They were identified by staining and biochemical methods as discussed by bouvet and grimont. Antibiotic resistance pattern of all isolates were checked by disc diffusion test, Kirby Bauer disc diffusion method. Pure bacterial culture suspended in buffer, standardized to turbidity and swabbed uniformly on Muller Hinton agar. Antibiotic discs were then placed on agar plate. Inhibition zones were compared with standard table of CLSI.Results:Ampicillin , Gentamicin, Tetracycline , Ceftazidim, , Amikacine , Meropenem , Colistin and Streptomycin were used in this experiment and majority (99%) of Acinetobacter baumannii strains were resistant to meropenem and mostly they were sensitive to colistin and some isolates were recognized as Multi drug resistant (MDR) A.baumannii.Conclusion:During last decades, resistance of A.baumannii to different antibiotics was elevated, according to our experiment and similar researches; it was shown each isolate stayed susceptible to one or more tested and common antibiotics. But, according to possibly transformation of resistant genes to the other strains, reconsideration in antibiotic consumption patterns should be highlighted in better ways.

نویسندگان

Elnaz Arzhang

Department of Microbiology,Kerman Branch,Islamic Azad University,Kerman,iran