DETERMINATION OF ANTIBIOTIC RESISTANCE AND FREQUENCY EXTENDED-SPECTRUM BETA LACTAMASES IN ACINETOBACTER BAUMANNII STRAINS ISOLATED FROM PATIENTS HOSPITALIZED IN BURNS WARD IN TEHRAN

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 355

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شناسه ملی سند علمی:

MEDISM19_115

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:Acinetobacter baumannii is an opportunistic and rapidly appearing pathogen that is a major contributor to hospital infections world wide. Which causes urinary tract infections, burns and infections in hospitals due to Acinetobacter baumannii drug resistance. The aim of this study was to evaluate the prevalence of extended-spectrum beta-lactamases (ESBL) in patients hospitalized in the burn ward of the Erfan Hospital in Tehran.Methods:In this study, 23 strains of Acinetobacter baumannii were isolated from patients in the burn ward of Erfan Hospital and identified by biochemical tests. resistance commonly used antibiotics was determined by the Kirby-Bauer method. To study ESBL production, a combination and double discs was performed.Results:The antibiotic resistance rates used in this study were: Cefotaxime and Ceftriaxone (98%), Ceftazidime (96%), Meropenem and Imipenem (94%), and Piperacillin+ Tazobactam (90%). And the abundance of ESBL production (4.34%) is identified.Conclusion:In this study Only (4.34%) of isolates have been produced ESBL. Therefore, in these bacteria other mechanisms than broad-spectrum beta-lactams such as secreted pumps and changes in purines cause resistance, which rapid identification plays an important role in preventing their spread.

نویسندگان

Farid Tarafdar

Msc Student of Microbiology, Department of Microbiology, Ahar branch, Islamic Azad University, Ahar, Iran

Behboud Jafari

Assistant professor, Department of Microbiology, Ahar branch, Islamic Azad University, Ahar, Iran