The associatin of sex protein receptors and Sex Steroid metabolic enzymes genes polymorphisms with breast cancer risk
محل انتشار: سیزدهمین کنگره بین المللی سرطان پستان
سال انتشار: 1396
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 449
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شناسه ملی سند علمی:
ICBCMED13_007
تاریخ نمایه سازی: 2 تیر 1397
چکیده مقاله:
Introduction & aim: Breast cancer is a common disease between women throughout the world that is a great factor to demise women. There are many different genes to outbreak of the disease, some polymorphisms of these genes increase susceptibility to breast cancer in some ethnicity. Methods: This study has checked out the effects of different gene polymorphisms of Sex Steroid metabolic proteins associated with increasing the risk of breast cancer that were recently reported from candidate genes by electronic literature search.Results and Conclusion: This study suggests strong influences of ER-α, ER-β, PGR, PXR and some CYPs genes polymorphisms in breast cancer susceptibility in especially in African American population.
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نویسندگان
Somayeh Jahandoost
MSc. Department of Genetics and Molecular Medicine, Zanjan University of Medical Sciences, Iran
Pourandokht Farhanghian
Corresponding author, PhD. Assistant professor, School of Allied Medicine, Tehran University of Medical Sciences, Tehran, Iran
Sakineh Abbasi
Corresponding author, PhD. Assistant professor, School of Allied Medicine, Tehran University of Medical Sciences, Tehran, Iran