Triple-Negative Breast Cancer Survival in Kurdish Patients

Introduction: Triple negative breast cancers (TNBCs) are defined as the lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2). In this study we evaluated survival and clinicopathologic characteristics in Kurdish patients in Iran with TNBC. Methods: Between of 2009 and 2015, 58 patients with TNBC referred to Department ofRadiation Oncology in Imam Reza Hospital, Kermanshah, Iran. We analyzed sex, age, type of pathology, grade tumor, laterality, stage, tumor size, overall survival and vascular, perineural, margin and skin invasion. The OS was plotted with GraphPad Prism 5 software and IBM SPSS version 19 Results: The mean age for the patients at diagnosis was 44.29(±9.29), 100% female. Mean tumor size was 3.05 cm (range, 0.6-6 cm). Grade III was the most grades in TNBC (50%). Fifty four patients (93.1%) had invasive ductal carcinoma, one (1.7%) had invasive lobular carcinoma and 3 (5.2%) had invasive medullary. Sex, nineteen, twenty one and twelve patients were in stage I, II, III and IV, respectively. Twenty sex patients did not have vascular invasion (n=46). Twenty sex patients did not have perineuralinvasion (n=42). Forty two patients did not have margin invasion (n=50). Forty five patients did not have skin invasion (n=50).Overall survival for all of patients that the overall survival rate was 62%. Conclusion: Information about TNBC is low in Iran, especially in west of Iran. We need more research in this area because TNBC had a poorer overall survival than those without

کلیدواژه ها:

Kurdish ، Overall Survival ، TNBC