Effects of Lavendula officinalis aqueous extract on oogenesis Balb/C adult femal mouse.

Background: Lavendula Officinalis has different treating effects including sedative and antiviral effects.However, there is no previous investigation on the effect of lavender on oogenesis,we aimed to assess the effect of lavendula extract on oogenesis of mature female mice(Balb/C).Methods: After preparation of aqueous extract, experiments was on 50 mice with selected doses:6,12,18g/kg.bw.injections were done for 12 days. Results were compared with the control group and sham. For reliability of above results, experiences were repeated 3 times. Data was checked with SPSS 20 software and Duncan post test and ANOVA subject to (PResult: According to the results,the histological Results showed changes that the injection of aqueous extract of lavendula decreased the large and small diameters of ovary in the first and second experiment groups p Conclusion: it seems that lavendula can be used as a herbal contraceptive method regarding its effect.Although,higher dosage of lavendula may affect the oogenesis, it seems that it can treat different diseases,Therefore,performing further investigations on its effect by different route of administering and dosages can be recommended

کلیدواژه ها:

follicle ، mice ، oogenesis ، Balb/C ، lavender ، ovary ، reproductive system