The study of anti-Mullerian hormone and adiponectin in polycystic ovarian syndrome

Background: Polycystic ovary syndrome (PCOs) is the most common endocrine disorder in women of reproductive age with a prevalence of 4-18%. PCOs is one of the outstanding matters of endocrinological and gynecological investigation due to its complex pathogenesis and its multiple clinical expressions. The aim of this study was determination of anti-Mullerian hormone and adiponectin in PCOs.Methods: To explore the possible roles of anti-Mullerian Hormone (AMH) and adiponectin in PCOs women, we review the available studies published until 2015. For this purpose, the articles in databases Pubmed and Google scholar in connection with the title of the study were searched.Result: A number of studies show lower adiponectin levels and higher concentrations of AMH in PCOs women. Our review finding reveals that BMI increasing has direct effect on AMH and adiponectin levels. Insulin resistance plays an important role in increasing serum AMH in PCOs.Conclusion: Serum AMH levels decline with obesity. Obesity is associated with reduced adiponectin levels. Low level of adiponection can be related to pathogenesis of PCOs and its related complications. Adiponectin may be a link between hormonal dysfunction of adipose tissue related to obesity and decreased AMH secretion.

کلیدواژه ها:

adiponectin ، Polycystic ovarian syndrome ، Anti-Mullerian hormone