The results of pregnancies after family balancing by pre implantation genetic screening and its relation with couple’s age

Background: Social utilization of pre-implantation genetic screening (PGS), for family balancing, is increasing, therefore it is necessary to follow-up the health and outcome of fertilization and newborn’s birth followed PGS. The aim of this study was to evaluate the outcome of fertilization after family balancing by PGS and the relation between age of parents and clinical outcome.Methods: This was a retrospective descriptive correlative study conducted on 218 couples in Isfahan. Samples were selected through convenience sampling. The rate of chemical and clinical pregnancy and abortion, frequency of success in achieving desired sex, and mean of gestational age and weight of newborns were gathered through reviewing medical files and phone interviews. Data was analyzed using independent t test and pearson correlation test. Result: Rate of chemical and clinical pregnancy was 30.7% and 30.3% respectively, the rate of abortion was 26.9%, the frequency of success in achieving the desired sex was 100%, and mean of gestational age and weight of newborns was 3260 (616) kg and 37.7 (2.07) weeks respectively. There was no significant relation between the age of parents and rate of abortion, rate of chemical and clinical pregnancy and newborn’s gestational weight. But there was a significant relation between the age of men and gestational age of newborns (P = 0.04).Conclusion: PGS method was 100% successful in achieving the desired sex, but relatively high rate of abortion could indicate the effect of PGS on the embryo development process which was related to gender of the pervious child in the family.

کلیدواژه ها:

Age ، Chemical pregnancy ، Iran ، Pre implantation genetic screening ، Pregnancy ، Abortion