Perturbation in Bon's Living Function Caused by Replacing Collagen Fibers With Carbon Nanotubes

Bone is a very dynamic living existent which continuously goes through a coupled process of resorption and formation , a process so- called bone remodeling. It is a well accepted , but undesirable fact that after maturation , bone's quality deteriorates by time . Therefore , a great need appears for fabricating artificial bone and / or improving the natural bone's mechanical properties. This necessity has attracted numerous researchers from diverse fields of bio-engineering . The composite - like structure of bone encourages researchers to look for a superior fiber for replacing bone's organic as a means of enhancing its properties . Carbon nanotubes (CNTs), due to their similarities with collagen fibers (CFs) and also outstanding mechanical properties , are apparently one suitable candidate for such an applicatio. However , the big differences between their mechanical properties with those of CFs, moreover the high sensitivity of bone sensor cells to exerted mechanical stimli , can raise a concern about the potential drawbcks of employing CNTs (instead of CFs) from the bone remodeling point of view, so , it is hypothesized here that application of CNTs, despite the fact that can considerably increases bone mechanical properties , may have a negative effect on the bone remodeling process, which is absolutely necessary for bone maintenance and health.

کلیدواژه ها:

Bone ، Remodeling ، Carbon nanotubes ، Collagen Fibers ، Strain Energy