Cancer Stem Cell

سال انتشار: 1396
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 507

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شناسه ملی سند علمی:

IPMCMED02_088

تاریخ نمایه سازی: 29 فروردین 1397

چکیده مقاله:

Cancer is a class of diseases caused by uncontrollable cell growth in parts of the body.Based on the available evidence, the underlying cause of cancer is a group of stem cells called cancer stem cells. Cancer stem cells secrete many substances such as protease enzymes which are the main reason of causing tumors.Based on studies of signaling pathways in cancers such as BMI1 / Wnt or beta-cat which have similar effects on self-renewal process of normal and cancerous stem cells, each population is sorted based on common pathways. Cancer stem cells are found in hematologic and Solid tumors including breast, brain, prostate, lung and liver cancer. The various strategies which have been expressed in Personalized Medicine led to provision a suitable treatment for each person.This includes: 1. targeted pharmacy (using of such substances as Liposomes, Nanotubes, and Nano gels). 2. Targeting the drug resistant genes and making the proper treatment for each person. 3. Destruction of stem cell niche

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نویسندگان

Vahidreza Esfehani

Islamic Azad University Medical Sciences of Tehran / Baqiyatallah University of Medical Sciences-Personalized Medicine Research Center

Mahsa Alikarami

Islamic Azad University Tehran Medical Branch / Baqiyatallah University of Medical Sciences-Personalized Medicine Research Center

Fatemeh Zahra Esfehani

Payame Noor University of Tehran East, Iran/ Baqiyatallah University of Medical Sciences- Personalized Medicine Research Center

Fatemeh Poureghbal

Islamic Azad University-Dezful Bbranch,iran/ Baqiyatallah University of Medical Sciences- Personalized Medicine Research Center