challenges and opportunities of Breast cancer personalized medicine

In fact, we have know the complexity of molecular pathogenesis of breast cancer the reasons could be related to diversity of populations in term of age, ethnicity and environment risk factors.Risk factors related to cancer progression include genetic reproduction,nutrition,Obesity and exposure to environment Emerging landscape of molecular biology of Breast cancer,represent afew dominant driver mutations reflecting special genes or pathway,Reavired for tumoorgenesis.for daily clinical management of cancer affected patients,personalized medicine is highly valuable goal Although we stiu.Need to expand our knowledge about molecular aspect of disease and its variety. Applied sciences use achieved information from bereast cancer biology to select genes and preventive targeted therapy methods, aswell as applying imovative drug designs and virtual biomarkers for clinical management of patient.The emerging picture of the molecular biology of breast cancer suggests that there are some predominant driver mutations that reflect specific genes or pathways as an event required for tumorigenicity.Personalized medicine for the routine clinical management of breast cancer patients is a lofty goal that will require expansion of our knowledge of the molecular underpinnings of this disease and its various subtypes,Applied science will harness the information generated related to the biology of breast cancer to select genes and pathways for development of targeted therapies and innovative drug designs and to investigate practical biomarkers for clinical management.

کلیدواژه ها:

Breast cancer ، personalized medicine ، molecular pathogenesis ، mutations ، clinical management