The role of Precision Medicine in controlling of OSCC according to ethnicity

In dealing with oral cancer, which has recently become one of the prevalent cancers in Asian societies, several factors have to be considered in targeting strategies.Because of the confrontation of various communities with various environmental, nutritional, and infectious factors that play a major role in oral cancer, race and ethnicity are one of the most important factors to be considered And the expression of should be explained genes according to that particular ethnicity.For example, in the OSCC disease, ABOBEC3B deletions can Significantly be seen as a prognostic factor due to inhibition of acquired immune system in a community with Taiwanese ethnicity that is more exposed to environmental and infectious factors. In this review article, the role of this protein in suppressing acquired immunity and the response of the inherent immune system to this extinction by increasing the expression of A3A has been attempted to identify this factor in the survival of patients with OSCC.It should be noted that for the targeted treatment of these patients (Personal Medicine), it is very important to pay attention to the type of gene expression in a particular ethnic group. That is why the information obtained from this article is different from the information available in the OSCC-TCGA data base

کلیدواژه ها:

oscc ، ABOBEC3B ، A3A ، Personal Medicine