A Review On Anticancer Activities Of Propolis

Cancer is an abnormal growth of cells in body that can lead to death. These cells are born due toimbalance in the body and by correcting that, the cancer might be treated.Today Cancer stands as amajor public health problem in world ,which makes it important to find a way to perfectly cure it,with making sure of the less side effects and best selectivity of the remedy. Our holly book,Quran,maintains a great respect for Bee and its products that names a chapter after it.in this chapter,Quran claims that there is a certain healing effect in bee products, which is the reason of choosingone of these products to study it’s anticancer effects in this article. Propolis which is produced bybees from the resin ,is collected from trees and shrubs.we have evidences of several uses of it intraditional medicine for treating different diseases.so far, propolis has been in many researchersdue to it’s antimicrobial, antifungal and antiviral activities .Researches have shown that it caninduce apopothosis in several tumor cells. This review summarizes the current knowledge ofanticancer activities of propolis,with the hope of finding a promising activity of it in cancertreatment. After studying different articles regarding mechanisms of propolis in it’s fight againstcancer, I found it’s most important pharmacologically active molecules are flavonoids and phenolicacids and their esters. These components lead to propolis anti-inflammatory andimmunomodulatory activities.moreover propolis is able to induce apoptosis pathways in cancercells, with CAPE and chrysin which are two main agents with antiproliferative effects.therefore,there is some hope of the possibility of finding a novel targeted therapy for cancer, as it canspecifically target tumor cells,so there would be less side effects.by having these sort of informationin hand, there might be a new era in cancer treatment in order to save millions of lives.