Porous Media Approach to Tumor Diagnosis in the Kidney under Uniaxial Time-Dependent Loading

This study proposed a new method for the tumor diagnosisembedded in the kidney based on a porous media approach.To this end, an in vitro experimental study was conducted onthe limb kidney by a robot-assisted device that exertedcompressive strain on the tissue surface with a constantvelocity. The tumor was simulated in a kidney sample byinserting an external mass inside the tissue while anotherkidney was healthy and normal. The resultant compressivestress versus the applied strain was recorded. Stress-straindata was used to extract the permeability of the healthy tissueand the mass-included tissue based on the Darcy’s Law.Results affirmed that existence of a concentrated mass as atumor greatly reduces the permeability of the tissue. Findingshave the potential to be used for tumor detection in the kidneytissue.