Effect of Systemic Granisetron in the Clinical Course of Spinal Anesthesia with Hyperbaric Bupivacaine for Outpatient Cystoscopy
محل انتشار: مجله علمی جراحی، دوره: 2، شماره: 1
سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 448
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شناسه ملی سند علمی:
JR_AJS-2-1_005
تاریخ نمایه سازی: 17 مرداد 1396
چکیده مقاله:
Background: The goals of this study are evaluation the effect of intravenous (IV) granisetron on the durationof sensory and motor block produced by intrathecal hyperbaric bupivacaine and also post-operative nausea andvomiting in patients undergoing outpatient cystoscopy.Methods: 62 patients, undergoing cystoscopy received either 3 mg IV granisetron or placebo 15 minutesbefore the spinal block. Sensory and motor block were assessed after the intrathecal injection of bupivacaineevery 2 minutes until the maximum block was achieved and thereafter every 15 minutes until recovery fromthe sensory and motor block.Results: Demographic data were not statistically different in the study groups. Duration of sensory and motorblock were also not statistically different between the study groups (P = 0.060 and P = 0.070 respectively). Nopatient in either group had vomiting. Seven patients in saline and zero patient in granisetron group had nauseathat was statistically significant (P = 0.040). Time to discharge after surgery was 243 ± 21 and 239 ± 24minutes in granisetron and control group respectively (P = 0.150).Conclusions: Systemic granisetron had no effect on the duration of sensory and motor block produced byspinal anesthesia with hyperbaric bupivacaine.© 2015 Tehran University of Medical Sciences. All rights reserved.Citation: Soltani-Mohammadi S, Esmaeili S, Saliminia A. Effect of Systemic Granisetron in the ClinicalCourse of Spinal Anesthesia with Hyperbaric Bupivacaine for Outpatient Cystoscopy. Acad J Surg, 2015;2(1-2): 18-22.
کلیدواژه ها:
Bupivacaine ، Granisetron ، Sensory block ، Motor block ، Anesthesia ، Spinal ، Outpatients ، Cystoscopy
نویسندگان
Sussan Soltani-mohammadi
Department of Anesthesiology, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran
Salimeh Esmaeili
Department of Anesthesiology, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran
Alireza Saliminia
Department of Anesthesiology, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran