Preparation Of N3-(4-chlorophenyl)-N4-cyclohexyl-3,4-dihydro-2-oxo-2H-chromene-3,4-dicarboxamide using Multi-component reaction

A mild and efficient tree component reaction was developed among para-chloroaniline, cyclohexylisocyanide and coumarin-3-carboxilicacid to prepare N3-(-4-chloro phenyl)-N4–cyclohexyl-3,4-dihydro-2- oxo-2H-chromen-3,4-dicarboxamide product. This one-pot reaction led to the formation of two amide groups with easy recovery of the desired product.

کلیدواژه ها:

coumarin- 3-carboxilicacid ، cylohexylisocyanide ، Multicomponent reaction