Chemoselectivity of S and N Nucleophiles Toward Pentachloropyridine

Site reactivity of some anions derived from 3,4-dihydropyrimidine-2(1H)-thiones with pentachloropyridine under basic conditions in dry CH3CN was investigated. The aromatic nucleophilic substitution of pentachloropyridine with 3,4-dihydropyrimidine-2(1H)-thione occurs at the 4-position of pyridine ring by sulfur site of 3,4- dihydropyrimidine-2(1H)-thione anion. Also the reaction of bis(dithiocarbamate salt) with pentachloropyridine in dry DMF was investigated that the aromatic nucleophilic substitution occurs at the 4-position of pyridine ring. The structures of all the compounds were confirmed by IR, 1H NMR and 13CNMR spectroscopy

کلیدواژه ها:

Pentachloropyridine ، Nucleophilic reaction ، Heterocycle