EFFICIENT AND GREEN SYNTHESIS OF BIS(INDOLYL)METHANES CATALYZED BY FE3O4@SIO2-IMID-PMAN MAGNETIC NANOCATALYST

Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by theelectrophilic substitution reaction of indole with aldehydes catalyzed by Fe3O4@SiO2-imid-PMAn wasdescribed. Simple work-up procedure, shorter reaction times, excellent yields, avoiding hazardousorganic solvents, and reusability of the catalyst are the most obvious advantages of this method. Also,the catalyst can be easily recovered by a magnetic field and reused for six consecutive reaction cycleswithout significant loss of activity.

کلیدواژه ها:

Bis(indolyl)methanes ، Indole ، Aldehydes ، Green synthesis ، Multi-component reactions ، Magnetic nanoparticles ، Magnetic separation