Antibacterial properties of salep-based silver nanoparticles

There is a continuous effort being directed to synthesize novel silver nanoparticles containing products having both antibacterial properties and new functional attributes. Alsonew synthesis strategies have been continuously evolved to prepare nanoparticles with newer application. In the past twodecades, various types of methods have been employed for the synthesis of Ag and Au nanoparticles through reduction of their respective salts with chemical reducing agents, such ascitric acid, borohydride and organic compound N,Ndimethylformamide. The synthesis of metal nanoparticlesusing aforementioned reducing agents is a straight forward resulting into their derivatization with biomolecules and thus, has been extensively studied while metal nanoparticlesderivatized with polysaccharides has largely been overlooked. The polysaccharide- nanomaterial integration has recentlyemerged as an exciting research opportunity. Recently, there has been a report on the synthesis of silver nanoparticles usingpolysaccharide from Porphyra vietnamensis [1]. Gole and his coworkers used glucose as a reducing agent for synthesizing gold nanoparticles entrapped in the thermally evaporated fattyamine film. Raveendran et al. used b-D glucose as a reducing agent and starch as a capping agent to prepare starch/silvernanocomposite film. In another similar study chitosan and heparin were used as reducing and stabilizing agents for the synthesis of Au and Ag nanoparticles, respectively[2]. The studies on biogenic synthesis of silver nanoparticles are scanty. There is no report on the exploitation of polyvinylpyrolidin greafted onto salep (PVP-g-salep) as a reducing agent for silver nanoparticle formation followed by investigations on its nanocomposite for in vitro antibacterial property.