Morphology and pore size study of electrospun Polyurethane nanofibres using engineered collector

Electro-spinning is a simple, versatile, and useful technique for fabricating nanofibres from a rich variety of functional materials. Beside the many advantages of this method, small pore sizes of electrospun nanofibrous scaffolds is a main concern for tissue engineering applications as it hinders cell infiltration and ingrowth into the scaffolds. To increase pore size of electrospun polyurethane nanofibrous scaffolds, in this study, patterned collectors with different insulation substrates were applied. Morphology of electrospun nanofibrous scaffolds were investigated by scanning electron spectroscopy (SEM). Pore sizes and nanofibre diameters were measured by analyzing SEM images. Obtained results showed that by increasing the thickness of insulation part, the diameter of nanofibers decreased slightly and pore size increased significantly